Human DSG2(50-609) Protein, His Tag

11943

Size：100 μg Price：$ 389 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11943

Product Name: Human DSG2(50-609) Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: CDHF5;HDGC

Target: DSG2

UNIPROT ID: Q14126

Description: Recombinant Human DSG2(50-609) Protein with C-terminal 6xHis tag

Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 63.3 kDa after removal of the signal peptide. The apparent molecular mass of DSG2(50-609)-His is approximately 70-100 kDa due to glycosylation.

Molecular Characterization: DSG2(Ala50-Gly609) 6×His tag

Purity: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human DSG2(50-609) Protein, His Tag on SDS-PAGE under reducing condition.

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Human DSG2(50-609) Protein, His Tag

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