Human ENPP2 Protein, His Tag

11976

Size：100 μg Price：$ 389 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 11976

Product Name: Human ENPP2 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: ATX;NPP2;ATX-X;PDNP2;LysoPLD;AUTOTAXIN;PD-IALPHA

Target: ENPP2

UNIPROT ID: Q13822

Description: Recombinant Human ENPP2 Protein with N-terminal 6xHis tag

Background: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 94.5 kDa after removal of the signal peptide. The apparent molecular mass of His-ENPP2 is approximately 100-130 kDa due to glycosylation.

Molecular Characterization: 6×His tag ENPP2(Asp49-Ile863)

Purity: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Human ENPP2 Protein, His Tag on SDS-PAGE under reducing condition.

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Human ENPP2 Protein, His Tag

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