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Human IL-20RA (C-Fc) Protein

12069

Size:50 μg Price:$ 289 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     12069
Product Name:   Human IL-20RA (C-Fc) Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Interleukin-20 Receptor Subunit Alpha;IL-20 Receptor Subunit Alpha;IL-20R-Alpha;IL-20RA;Cytokine Receptor Class-II Member 8;Cytokine Receptor Family 2 Member 8;CRF2-8;IL-20R1;ZcytoR7;IL20RA
Target:    IL-20RA
UNIPROT ID:    Q9UHF4
Description:    Recombinant Human Interleukin-20 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Val30-Lys250 is expressed with a Fc tag at the C-terminus.
Background:     Interleukin-20 Receptor Subunit a (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide, a 221 amino acid extracellular domain with two fibronectin type-III domains, a 24 amino acid transmembrane region, and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB, and the complex serves as a receptor for IL19, IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.
Species/Host:    HEK293
Molecular Weight:    52.4 KDa
Molecular Characterization:    Not available
Purity:    Greater than 95% as determined by reducing SDS-PAGE.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
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