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Human FGF-12 Protein

12067

Size:50 μg Price:$ 255 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     12067
Product Name:   Human FGF-12 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Fibroblast Growth Factor 12;FGF-12;Fibroblast Growth Factor Homologous Factor 1;FHF-1;Myocyte-Activating Factor;FGF12;FGF12B;FHF1
Target:    FGF-12
UNIPROT ID:    P61328-2
Description:    Recombinant Human Fibroblast Growth Factor 12 is produced by our E.coli expression system and the target gene encoding Met1-Thr181 is expressed.
Background:     Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
Species/Host:    E.coli
Molecular Weight:    20.45 KDa
Molecular Characterization:    Not available
Purity:    Greater than 95% as determined by reducing SDS-PAGE.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
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