Human IL-3 (N-6His) Protein

12082

Size：50 μg Price：$ 365 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 12082

Product Name: Human IL-3 (N-6His) Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: Interleukin-3;IL-3;Hematopoietic Growth Factor;Mast Cell Growth Factor;MCGF;Multipotential Colony-Stimulating Factor;P-Cell-Stimulating Factor;IL3

Target: IL-3

UNIPROT ID: P08700

Description: Recombinant Human Interleukin-3 is produced by our E.coli expression system and the target gene encoding Ala20-Phe152 is expressed with a 6His tag at the N-terminus.

Background: Interleukin-3 (IL-3) is a potent growth promoting cytokine. IL-3 can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. IL-3 exerts its biological function through binding to specific cell surface receptors. The amino acid sequences of this protein among different species share relatively low identity and its activity is highly species-specific. IL-3 has also been shown to possess neurotrophic activity, and is thought to be associated with neurologic disorders.

Species/Host: E.coli

Molecular Weight: 16.6 KDa

Molecular Characterization: Not available

Purity: Greater than 95% as determined by reducing SDS-PAGE.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.	Figure 2. Loaded Human IL-3RA-Fc on Protein A Biosensor, can bind Human IL-3 with an affinity constant of 3.89uM as determined in BLI assay.
Figure 3. Loaded Human IL-3RA-Fc-Avi on Protein A Biosensor, can bind Human IL-3 with an affinity constant of 3.74 uM as determined in BLI assay.

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Human IL-3 (N-6His) Protein

Human CLDN6 Full Length Protein

Human CB1 Full Length Protein

Human CCR4 Full Length Protein

Human OR2H1 Full Length Protein

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