Mouse CD47 Protein, hFc Tag

12136

Size：100 μg Price：$ 389 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: 12136

Product Name: Mouse CD47 Protein

Size : 10 µg, 50 µg and 100 µg

Synonyms: 9130415E20Rik;AA407862;AI848868;AW108519;B430305P08Rik;IAP;Itgp

Target: CD47

UNIPROT ID: Q61735

Description: Recombinant mouse CD47 protein with C-terminal human Fc tag

Background: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection (By similarity).[UniProtKB/Swiss-Prot Function]

Species/Host: HEK293

Molecular Weight: The protein has a predicted molecular mass of 40.0 kDa after removal of the signal peptide.The apparent molecular mass of mCD47-hFc is approximately 55-70 kDa due to glycosylation.

Molecular Characterization: Mouse CD47(Gln19-Lys140) hFc(Glu99-Ala330)

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.

Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1.Mouse CD47 Protein, hFc Tag on SDS-PAGE under reducing condition.

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Mouse CD47 Protein, hFc Tag

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