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Size:100 μg Price:$ 389 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 12133 |
Product Name: Mouse CD28 Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: CD28;Tp44 |
Target: CD28 |
UNIPROT ID: P31041 |
Description: Recombinant mouse CD28 protein with C-terminal human Fc tag |
Background: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.[UniProtKB/Swiss-Prot Function] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 41.2 kDa after removal of the signal peptide.The apparent molecular mass of mCD28-hFc is approximately 55-70 kDa due to glycosylation. |
Molecular Characterization: Mouse CD28(Asn20-Lys149) hFc(Glu99-Ala330) |
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Mouse CD28 Protein, hFc Tag on SDS-PAGE under reducing condition. |
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