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Mouse CD28 Protein, hFc Tag

12133

Size:100 μg Price:$ 389 Brand:NewEast Place of Origin:USA Immunogen:

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Product Description Reference citations(0) Related Products
Cat.#:     12133
Product Name:   Mouse CD28 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CD28;Tp44
Target:    CD28
UNIPROT ID:    P31041
Description:    Recombinant mouse CD28 protein with C-terminal human Fc tag
Background:     Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.[UniProtKB/Swiss-Prot Function]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 41.2 kDa after removal of the signal peptide.The apparent molecular mass of mCD28-hFc is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    Mouse CD28(Asn20-Lys149) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse CD28 Protein, hFc Tag on SDS-PAGE under reducing condition.
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