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Canis lupus familiaris ANXA2 Protein, His Tag

12124

Size:50 μg Price:$ 739 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     12124
Product Name:   Canis Lupus Familiaris ANXA2 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   Annexin A2;Annexin-2
Target:    ANXA2
UNIPROT ID:    Q6TEQ7
Description:    Recombinant canis ANXA2 protein with C-terminal 6xHis tag
Background:     This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms. [provided by RefSeq, Dec 2019]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 39.3 kDa after removal of the signal peptide. The apparent molecular mass of dANXA2-His is approximately 35-55 kDa due to glycosylation.
Molecular Characterization:    ANXA2(Ser2-Asp339) 6×His tag
Purity:    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Canis ANXA2 Protein, His Tag on SDS-PAGE under reducing condition.
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