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Mouse BAFF Protein, hFc Tag

12196

Size:100 μg Price:$ 659 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     12196
Product Name:   Mouse BAFF Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   B-cell-activating factor;CD257;Tnfsf13b;Baff
Target:    BAFF
UNIPROT ID:    Q9WU72
Description:    Recombinant mouse BAFF protein with N-terminal human Fc tag
Background:     Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.[UniProtKB/Swiss-Prot Function]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 46.8 kDa after removal of the signal peptide. The apparent molecular mass of hFc-mBAFF is approximately 40-55 kDa due to glycosylation.
Molecular Characterization:    hFc(Glu99-Ala330) Mouse BAFF(Ala127-Leu309)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse BAFF Protein, hFc Tag on SDS-PAGE under reducing condition.
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