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Mouse CD200 Protein, hFc Tag

12178

Size:100 μg Price:$ 550 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     12178
Product Name:   Mouse CD200 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   MRC OX-2 antigen;Mox2
Target:    CD200
UNIPROT ID:    O54901
Description:    Recombinant mouse CD200 protein with C-terminal human Fc tag
Background:     This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 48.7 kDa after removal of the signal peptide. The apparent molecular mass of mCD200-hFc is approximately 55-70 kDa due to glycosylation.
Molecular Characterization:    Mouse CD200(Gln31-Gly232) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse CD200 Protein, hFc Tag on SDS-PAGE under reducing condition.
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