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Mouse B7-1 Protein, hFc Tag

12168

Size:100 μg Price:$ 569 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:     12168
Product Name:   Mouse B7-1 Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   B7;CD80
Target:    B7-1
UNIPROT ID:    Q00609
Description:    Recombinant mouse B7-1 protein with C-terminal human Fc tag
Background:     The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
Species/Host:    HEK293
Molecular Weight:    The protein has a predicted molecular mass of 49.8 kDa after removal of the signal peptide. The apparent molecular mass of mB7-1-hFc is approximately 70-100 kDa due to glycosylation.
Molecular Characterization:    Mouse B7-1(Val38-Lys245) hFc(Glu99-Ala330)
Purity:    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure 1. Mouse B7-1 Protein, hFc Tag on SDS-PAGE under reducing condition.
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