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Size:100 μg Price:$ 389 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: 12279 |
Product Name: Human GPR132 Protein |
Size : 10 µg, 50 µg and 100 µg |
Synonyms: G2A |
Target: GPR132 |
UNIPROT ID: Q9UNW8 |
Description: Recombinant human GPR132 Protein with C-terminal human Fc tag |
Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Species/Host: HEK293 |
Molecular Weight: The protein has a predicted molecular mass of 30.9 kDa after removal of the signal peptide. The apparent molecular mass of GPR132-hFc is approximately 35-55 kDa due to glycosylation. |
Molecular Characterization: GPR132(Met1-Leu45) hFc(Glu99-Ala330) |
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human GPR132 Protein, hFc Tag on SDS-PAGE under reducing condition. |
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